22 drugs in the Diabetes family lose patent protection between 2026 and 2031. The family comes from the WHO ATC classification of each drug's ingredient; it is a filter, not a claim about any drug's approved indication.
This is the earliest date a generic could enter; it is not a guarantee one will. We calculate it as the later of the last patent the company listed with the FDA and the last regulatory exclusivity. Companies often reach settlement agreements with generic makers for a different date, and those agreements are not public in this data.
Juvisync (simvastatin; sitagliptin phosphate)Merck Sharp AND Dohme · 12 patents · October 11, 2026
Janumet XR (metformin hydrochloride; sitagliptin pho)Merck Sharp AND Dohme · 6 patents · May 24, 2027
Januvia (sitagliptin phosphate)Merck Sharp AND Dohme · 6 patents · May 24, 2027
Duetact (glimepiride; pioglitazone hydrochloride)Takeda Pharmaceuticals USA · 4 patents · June 8, 2028
Bydureon (exenatide synthetic)Astrazeneca AB · 72 patents · September 21, 2028
Onglyza (saxagliptin hydrochloride)Astrazeneca AB · 2 patents · November 30, 2028
Janumet (metformin hydrochloride; sitagliptin pho)Merck Sharp AND Dohme · 8 patents · January 21, 2029
Actoplus MET (metformin hydrochloride; pioglitazone hy)Takeda Pharmaceuticals USA · 4 patents · February 3, 2029
Kazano (alogliptin benzoate; metformin hydrochlo)Takeda Pharmaceuticals USA · 4 patents · May 24, 2029
Oseni (alogliptin benzoate; pioglitazone hydroc)Takeda Pharmaceuticals USA · 12 patents · June 4, 2029
Nesina (alogliptin benzoate)Takeda Pharmaceuticals USA · 6 patents · June 16, 2029
Dates from the FDA Orange Book, the official record of which patents cover
which approved drug; updated monthly. Facts only, not investment advice. Verify against the
Orange Book and primary filings. pdufa.bio is not affiliated with the FDA.
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