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2026 FDA PDUFA Calendar

Updated ·next FDA decision on the calendar

This page lists 97 FDA decision dates covering June 2026 to December 2026. 41 are still ahead, and 56 have been decided and are marked with the outcome. Each date comes from an FDA notice or a company filing, and where the source gives only a month or a quarter we say so instead of inventing a day.

A PDUFA date is the FDA's target date to complete review of a drug application, set under the Prescription Drug User Fee Act. It is a goal, not a promise: the agency can act before the date, on it, or after it.

A standard review carries a 10-month goal from the FDA's acceptance of the application; a priority review carries a 6-month goal. If the sponsor submits a major amendment during review, the FDA can extend the goal date by 3 months.

The FDA does not publish an official, forward-looking PDUFA calendar. Every date on this page comes from a company filing, press release or FDA notice, and each row links its source.

Of the 29 FDA decisions in 2026 on this site with both a sourced goal date and a sourced action date, 19 came before the goal date, 7 landed on it, and 3 came after. The largest early margin was 108 days (Relacorilant + nab-paclitaxel - (ROSELLA), Mar 25). Full record: FDA decision timing.

20 of the 56 decided rows on this page are archive decision records with no row in the API dataset; the API's 39 Decided rows in this window cover the other 36, counting a partner-held application once per listed ticker. Each archive row links its own sourced decision page.

On or around the goal date the FDA typically either approves the application or issues a Complete Response Letter explaining what stands in the way of approval. Decided rows below state the outcome in words and link the decision record.

Upcoming FDA PDUFA dates, updated September 20, 2026

Every upcoming FDA decision (PDUFA) date, drug, company, indication, run-up history, and market-cap cohort base rates. Tap any name for the full facts.
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Subscribing keeps it current: new dates and changes arrive automatically. 120 entries have a confirmed date and appear on that single day. 329 are guided only to a month or quarter, so they span that whole window and are prefixed with ~. We do not place an estimate on a specific day, because in a calendar app a guess looks exactly like a confirmed FDA date.
Run-up context, measured from a uniform T-120 baseline. Across 1,852 FDA decisions since 2020, the median peak gain from 120 trading days out was 17.9%, while the median move from T-120 to the day before the decision was 2.1%. The gap between those two numbers is the point: most of the move happens before the decision and is usually given back. 96% of events have a full T-120 window; the rest are excluded rather than back-filled. Full study. Past behaviour, not a forecast, and not investment advice.
Where 2026’s decisions clusterLargeMidSmallMicroNanoJULAUGSEPOCTNOVDECWeek of Jul 27 · 3 decisions · 1 Micro, 1 Small, 1 Large CAPR OTLK VTRS3Week of Aug 3 · 1 decision · 1 Large MRNAWeek of Aug 10 · 1 decision · 1 Mid LNTHWeek of Aug 17 · 6 decisions · 1 Small, 1 Mid, 2 Large, 2 Unlisted BMY BNTX CAPR CTMX EVAX RARE6Week of Aug 24 · 5 decisions · 1 Small, 4 Large GILD JAZZ ONC RPRX ZYME5Week of Aug 31 · 1 decision · 1 Large REGNWeek of Sep 7 · 1 decision · 1 Mid TLXWeek of Sep 14 · 3 decisions · 2 Mid, 1 Large NUVL RARE RPRX3Week of Sep 21 · 3 decisions · 1 Mid, 1 Large, 1 Unlisted INCY IONS MIRM3Week of Sep 28 · 5 decisions · 1 Nano, 1 Mid, 2 Large, 1 Unlisted BFRI PFE PTGX ROIV TAK5Week of Oct 5 · 1 decision · 1 Large MRKWeek of Oct 12 · 1 decision · 1 Large VTRSWeek of Oct 19 · 1 decision · 1 Small PHARWeek of Oct 26 · 4 decisions · 1 Micro, 1 Mid, 2 Large AGIO GSK INO IONS4Week of Nov 9 · 3 decisions · 1 Nano, 2 Large BTAI CYTK SMMT3Week of Nov 16 · 1 decision · 1 Small SVRAWeek of Nov 23 · 2 decisions · 1 Mid, 1 Large BBIO NUVLWeek of Nov 30 · 6 decisions · 1 Mid, 5 Large BAYRY COGT EXEL REGN RHHBY VRTX6Week of Dec 7 · 2 decisions · 1 Small, 1 Mid ANAB VNDAWeek of Dec 14 · 1 decision · 1 Large RHHBYWeek of Dec 21 · 2 decisions · 2 Mid MLYS PRAXWeek of Dec 28 · 1 decision · 1 Mid COGT54 scheduled FDA decisions across 25 weeks, stacked by market-cap tier · plus 12 more dated only to Q4. Hover a bar for the week’s tickers.
June 2026

23 FDA goal dates in June 2026; 23 already decided, each row linking its source, updated September 20, 2026.

BMY · 2026-06-01
Approved: Camzyos (mavacamten) - (SCOUT-
CING · 2026-06-02
CRL: CTx-1301 (fixed dose, pediatri
AMRX · 2026-06-04
Approved: Romidepsin injection solution,
PFE · 2026-06-08
Approved: HYMPAVZI (marstacimab)
ZVRA · 2026-06-08
Approved: MIPLYFFA (MY-PLY-FAH) (arimocl
XOMA · 2026-06-08
Approved: MIPLYFFA (MY-PLY-FAH) (arimocl
LGND · 2026-06-08
Approved: MIPLYFFA (MY-PLY-FAH) (arimocl
LLY · 2026-06-09
Approved: EBGLYSS (lebrikizumab-lbkz) -
MRK · 2026-06-12
Approved: KEYTRUDA (pembrolizumab) and K
AZN · 2026-06-12 · ✓ Approved
Truqap: Dephosphorylated Phosphatase and Tensin…
BAYRY · 2026-06-15
Approved: AMBELVIST (gadoquatrane)
ABBV · 2026-06-16
Approved: JUVÉDERM - (SKINVIVE) (injecta
GSK / SPRO · 2026-06-17 · ✓ Approved
Tebipenem HBr (SPR994): Complicated urinary tract infection (cUTI)…
MRK · 2026-06-18
Approved: CAPVAXIVE (Pneumococcal 21-val
ACHV · 2026-06-20 · ✕ CRL
Cytisinicline: Smoking cessation of cigarettes
PFE · 2026-06-24
Approved: IBRANCE (palbociclib) in combi
GILD / MRK · 2026-06-24
Approved: Trodelvy (sacituzumab goviteca
IONS · 2026-06-24 · ✓ Approved
TRYNGOLZA (olezarsen): Severe hypertriglyceridemia
ABBV · 2026-06-26
Approved: SKYRIZI (risankizumab-rzaa)
VRDN · 2026-06-26 · ✓ Approved
Veligrotug (VRDN-001): Thyroid Eye Disease (TED)
UNCY · 2026-06-29 · ✕ CRL
Oxylanthanum Carbonate (OLC): Kidney disease
ARQT · 2026-06-29 · ✓ Approved
ZORYVE (roflumilast) Cream 0.3%: Plaque Psoriasis in Children Ages 2 to 5
LNTH · 2026-06-29 · ✕ CRL
LNTH-2501 (Gallium-68 edotreotide): Neuroendocrine tumors (NETs) in adult and…
July 2026

11 FDA goal dates in July 2026; 11 already decided, each row linking its source, updated September 20, 2026.

CRSP / VRTX · 2026-07-01
Approved: Casgevy (exagamglogene autotemcel)
VERA · 2026-07-07 · ✓ Approved
Atacicept: IgA Nephropathy
ALPMY / MRK / PFE · 2026-07-10 · ✓ Approved
KEYTRUDA (pembrolizumab) plus Padcev (enfortumab vedotin-ejfv): Muscle-invasive bladder cancer (MIBC)
CORT · 2026-07-11
Approved: Relacorilant + nab-paclitaxel - (ROSELLA)
BIIB · 2026-07-13 · ✓ Approved
LEQEMBI IQLIK (lecanemab-irmb): Early Alzheimer's disease (at-home initiation dose)
CELC · 2026-07-14 · ✓ Approved
REVTORPYK (gedatolisib): HR+/HER2- advanced breast cancer
MRK · 2026-07-16
Approved: Lipfendra (enlicitide): first oral PCSK9 inhibitor
OTLK · 2026-07-24
Approved: , LYTENAVA (bevacizumab-vikg): first FDA-approved ophthalmic bevacizumab for wet AMD
MNKD · 2026-07-24
Approved: FUROSCIX ReadyFlow Autoinjector (SCP-111)
OTSKY / CNS · 2026-07-24
Approved: Centanafadine: ADHD in children, adolescents, and adults
VTRS · 2026-07-30
Approved: MR-100A-01(Low dose estrogen weekly patch…: Contraception
August 2026

9 FDA goal dates in August 2026; 9 already decided, each row linking its source, updated September 20, 2026.

MRNA · 2026-08-05
Approved: mRNA-1010: Seasonal influenza in U.S. adults 50 years of…
REPL · 2026-08-06
Approved: TUDRIQEV (vusolimogene oderparepvec-wtpg): Unresectable advanced cutaneous melanoma after
LNTH · 2026-08-13
Approved: Florquinitau (MK-6240): Alzheimer's disease
BMY · 2026-08-17
Approved: iberdomide, daratumumab, and dexamethasone…: Relapsed/refractory multiple myeloma (RRMM)
RARE · 2026-08-23
Approved: DTX401 AAV gene therapy (pariglasgene…: Glycogen Storage Disease Type Ia (GSDIa)
JAZZ / ONC / ZYME · 2026-08-25
Approved: Ziihera (zanidatamab-hrii): First-line HER2-positive gastroesophageal…
RVMD · 2026-08-26
Approved: Rasonque (daraxonrasib)
GILD · 2026-08-27
Approved: Bictegravir and Lenacapavir: HIV
REGN · 2026-08-31
Approved: Garetosmab: Fibrodysplasia Ossificans Progressiva (FOP)
September 2026

13 FDA goal dates in September 2026; 11 already decided, each row linking its source, updated September 20, 2026. In September the FDA is due to decide on Zilurgisertib (INCY, Sep 26).

AZN · 2026-09-04
Approved: Etcamah (camizestrant)
TLX · 2026-09-11
Approved: TLX101-Px: Recurrent or progressive glioma (brain cancer)
LLY · 2026-09-18
Approved: Inluriyo (imlunestrant) with Verzenio (abemaciclib)
NUVL / RPRX · 2026-09-18
Approved: Zidesamtinib (NVL-520): ROS1 Non-small cell lung cancer (NSCLC)
ABEO / RARE · 2026-09-19
Approved: UX111: Sanfilippo syndrome type A (MPS IIIA)
MRK · 2026-09-21
WINREVAIR (sotatercept-csrk): Pulmonary arterial hypertension (PAH, WHO*…
IONS · 2026-09-22
Approved: Zilganersen (ION373): Alexander disease
INCY · 2026-09-26
Zilurgisertib (Mirum holds the NDA; Incyte licensed it out): FOP
BFRI · 2026-09-28
Approved: Ameluz (aminolevulinic acid hydrochloride)…: Basal cell carcinoma
SRRK · 2026-09-30
Approved: Apitegromab - (SAPPHIRE)
PFE / ROIV · 2026-09-30
Approved: Brepocitinib: Dermatomyositis (DM)
TAK · Q3 2026
Approved: Oveporexton (TAK-861-2001): Narcolepsy type 1 (NT1)
PTGX · Q3 2026
Approved: Rusfertide: Polycythemia vera
October 2026

7 FDA goal dates in October 2026; 1 already decided, each row linking its source, updated September 20, 2026. In October the FDA is due to decide on Bepirovirsen (GSK, Oct 26).

RHHBY · 2026-10-09
Tecentriq (atezolizumab) and Tecentriq…: Stage III colon cancer
MRK · 2026-10-10
Ifinatamab deruxtecan (DS-7300): Extensive-stage small cell lung cancer (SCLC)
RHHBY · 2026-10-15
Enspryng (satralizumab) - (thyroid eye disease)
IRD / VTRS · 2026-10-17
MR-141 (phentolamine ophthalmic solution…: Presbyopia
PHAR · 2026-10-24
Approved: Leniolisib: Activated phosphoinositide 3-kinase delta…
GSK · 2026-10-26
Bepirovirsen - (B-Well)
INO · 2026-10-30
INO-3107: HPV 6 and HPV 11-associated Recurrent…
November 2026

13 FDA goal dates in November 2026; 1 already decided, each row linking its source, updated September 20, 2026. In November the FDA is due to decide on BBP-418 (BBIO, Nov 27), Aficamten (CYTK, Nov 14), Mitapivat (AGIO, Nov 1), Deramiocel (CAPR, Nov 22) and MOLBREEVI (SVRA, Nov 22).

AGIO · 2026-11-01
Mitapivat (PYRUKYND) - (RISE UP)
CYTK · 2026-11-14
Aficamten - (MAPLE-HCM)
BTAI · 2026-11-14
IGALMI® (dexmedetomidine): Agitation associated with bipolar I or II…
SMMT · 2026-11-14
Ivonescimab plus platinum-doublet…: EGFR-mutated, locally advanced or metastatic…
CAPR · 2026-11-22
Deramiocel (CAP-1002) - (HOPE-3)
SVRA · 2026-11-22
MOLBREEVI (Molgradex): Autoimmune pulmonary alveolar proteinosis…
BBIO · 2026-11-27
BBP-418: Limb Girdle Muscular Dystrophy Type 2i…
GSK · 2026-11-27
Neladalkib (NVL-655) (formerly Nuvalent, NUVL): ALK non-small cell lung cancer (NSCLC)
COGT · 2026-11-30
Bezuclastinib + sunitinib - (PEAK)
VRTX · 2026-11-30
Povetacicept (ALPN-303): Lupus nephritis, IgA nephropathy
RHHBY · 2026-11-30
Giredestrant: Early breast cancer
REGN · Nov 2026
Cemdisiran + pozelimab (C5 combo) - (NIMBLE)
BAYRY · Nov 2026
Approved: HYRNUO (sevabertinib): HER2-mutated non-small cell lung cancer…
December 2026

21 FDA goal dates in December 2026, 8 of them dated only to the quarter, each row linking its source, updated September 20, 2026. In December the FDA is due to decide on MR-107A-02 (VTRS, Dec 27) and Imsidolimab (ANAB/VNDA, Dec 12).

EXEL · 2026-12-03
XL092 with atezolizumab: Colorectal Cancer (CRC)
ANAB / VNDA · 2026-12-12
Imsidolimab (ANB019): Generalized pustular psoriasis
CORT · 2026-12-17
Relacorilant - (GRACE resubmission)
RHHBY · 2026-12-18
Giredestrant in combination with everolimus: ER-positive advanced breast cancer
MLYS · 2026-12-22
Lorundrostat: Uncontrolled hypertension (uHTN) or resistant…
GILD · 2026-12-23
Anito-cel (anitocabtagene autoleucel)
PRAX · 2026-12-27
Relutrigine (PRAX-562): Developmental epileptic encephalopathies…
VTRS · 2026-12-27
MR-107A-02: Pain
COGT · 2026-12-30
Bezuclastinib: Non-Advanced Systemic Mastocytosis
RHHBY · Q4 2026 (est.)
Lunsumio + Polivy: 2L+ Diffuse Large B-Cell Lymphoma (DLBCL)
ABBV · Q4 2026 (est.)
RINVOQ (upadacitinib): Non-segmental vitiligo (NSV)
GILD / MRK · Q4 2026 (est.)
Trodelvy (sacituzumab govitecan-hziy) plus…: Inoperable (unresectable) locally advanced or…
AZN · Q4 2026 (est.)
Gefurulimab: Generalised myasthenia gravis
NVS · Q4 2026 (est.)
Pluvicto (lutetium (177Lu) vipivotide…: End-stage prostate cancer
RHHBY · Q4 2026 (est.)
Gazyva: Systemic Lupus Erythematosus
LLY · Q4 2026 (est.)
Tirzepatide: Cardiovascular outcomes
PFE · Q4 2026 (est.)
TUKYSA, trastuzumab, and pertuzumab: HER2+ Metastatic Breast Cancer
NVO · Dec 2026
AM833 (CagriSema): Obesity
ABBV · Dec 2026
Tavapadon: Early Parkinson’s disease
BAYRY · Dec 2026
KERENDIA (finerenone): Type 1 Diabetes and Chronic Kidney Disease
AZN · Dec 2026
Ultomiris (ravulizumab): Immunoglobulin A nephropathy

Companies on this page

Every company listed above, with its full catalyst history, past FDA decisions and measured run-up into each one.
ABBVACHVAGIOAMRXARQTAZNBAYRYBBIOBFRIBIIBBMYBTAICAPRCELCCINGCOGTCORTCRSPCYTKEXELGILDGSKINCYINOIONSJAZZLGNDLLYLNTHMLYSMNKDMRKMRNANUVLNVONVSOTLKOTSKYPFEPHARPRAXPTGXRAREREGNREPLRHHBYRVMDSMMTSRRKSVRATAKTLXUNCYVERAVNDAVRDNVRTXVTRSXOMAZVRA

Questions

How many FDA decisions are scheduled in 2026?

97 FDA decision dates are on this calendar, covering June 2026 to December 2026, and 41 are still ahead as of September 20, 2026.

When is the next FDA decision?

MRK's WINREVAIR on September 21, 2026, tomorrow.

How often is this calendar updated?

Daily. Dates come from FDA announcements, sponsor press releases and SEC filings, and every date on the page links its source.

What happens on a PDUFA date?

The FDA approves the application, issues a Complete Response Letter, or extends the review. What a PDUFA date is.