Daily close, T-120 (6/18/25) through T+5. Run-up high $1109.94 on 11/26/25, low $625.65 on 8/12/25 (T-120 to T-1). FDA decision 12/3/25. Historical price action, not a forecast.
Positioning before the decision
On Nov 19, 2025, 14 days before the decision date, at-the-money options priced a move of ±6.1% through Dec 5, 2025 (the first listed expiry after the decision; ATM implied volatility 36%). The stock closed -1.2% at the first close across the decision and -6.1% five trading days on. A straddle priced weeks out covers ordinary movement plus the event, so this is the move the options market priced through that expiry, not the event-implied move alone. How this compares across 1,000+ decisions.
Yes. The FDA approved the application for Jaypirca (pirtobrutinib) on December 3, 2025. The primary source is linked on this page.
What was Jaypirca (pirtobrutinib) under FDA review for?
The application covered Relapsed or refractory CLL/SLL. The FDA approved the application on December 3, 2025.
How did LLY stock react to the FDA decision?
On the decision day LLY moved -1.2%. That is the recorded reaction to this specific event -- historical measurement, not a prediction, and not investment advice.