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DNLI FDA decision: Mar 25, 2026

Updated ·next FDA decision on the calendar
✓ APPROVED

Denali Therapeutics Inc., AVLAYAH (Tividenofusp alfa) - (COMPASS) · Hunter syndrome MPS II.

Run-up into the decision (T-120 → T+5)

PDUFA 3/25/26$22.74$14.4110/8/25
Daily close, T-120 (10/8/25) through T+5. Run-up high $22.74 on 2/3/26, low $14.41 on 11/13/25 (T-120 to T-1). FDA decision 3/25/26. Historical price action, not a forecast.

Key facts

FDA decision date2026-03-25
OutcomeApproved
Drug / candidateAVLAYAH (Tividenofusp alfa) - (COMPASS)
CompanyDenali Therapeutics Inc.
120-day run-up (T-120→T-1)+40.6%

Questions

Was AVLAYAH (Tividenofusp alfa) - (COMPASS) approved by the FDA?

Yes. The FDA approved the application for AVLAYAH (Tividenofusp alfa) - (COMPASS) on March 25, 2026. The primary source is linked on this page.

Which company is behind AVLAYAH (Tividenofusp alfa) - (COMPASS)?

AVLAYAH (Tividenofusp alfa) - (COMPASS) is a Denali Therapeutics Inc. (DNLI) program. The FDA decision came on March 25, 2026; the company's own announcement is linked on this page.

How did DNLI stock trade into the FDA decision?

Measured over the 120 trading days before the decision (T-120 to T-1), DNLI moved +40.6%. That is the recorded price path into this specific event -- historical measurement, not a prediction, and not investment advice.